I tried this the other day running Nyxt and StumpWM from the same repl. Nyxt froze and I couldn't kill the thread from the repl. Then StumpWM froze and I had to switch to a different TTY and kill the whole xsession... That was fun, but there's definitely some work that needs to be done.
The properly lispy thing would have been to debug Nyxt from the working repl, but the thread in question was non-responsive, so I don't know how you'd debug in the thread. (I'm a noob though who mostly hacks in Clojure, so maybe there was a better way).