My interests lie in the fields of molecular biology, genetics and evolution of fish. Large multi-gene families and whole genome duplications from salmonid species are used to examine molecular mechanisms of change (gene conversion, duplication, deletion, mutation, etc.) as well as population genetic dynamics. Broad molecular evolutionary problems are examined using highly multidisciplinary laboratory and bioinformatic approaches.
Clinical Cancer
Advanced Cell Biology
Christensen, KA, EB Rondeau, DR Minkley, JS Leong, CM Nugent, RG Danzmann, MM Ferguson, A Stadnik, RH Devlin, R Muzzerall, M Edwards, WS Davidson, BF Koop. 2018. The Arctic charr (Salvelinus alpinus) genome and transcriptome. PLoS ONE 13(9): e0204076
Messmer, A, JS Leong, EB Rondeau, A Mueller, CA Despins, DR Minkley, MP Kent, S Lien, B Boyce, D Morrison, MD Fast, JD Norman, RG Danzmann, BF Koop. 2018. A 200K SNP chip reveals a novel Pacific salmon louse genotype linked to differential efficacy of emamectin benzoate. Marine Genomics 40; 45-57
Christensen KA, JS Leong, D Sakhrani1, CA Biagi1, DR Minkley, RE Withler, EB Rondeau, BF Koop and RH Devlin. 2018. Chinook salmon (Oncorhynchus tshawytscha) genome and transcriptome. PLoS ONE 13(4):e0195461
Le Luyer J, M Laporte, TD Beacham, KH Kaukinen, RE Withler, JS Leong, EB Rondeau, BF Koop, L Benatchez. 2017. Parallel epigenetic modifications induced by hatchery rearing in a Pacific Salmon. Proc Natl Acad Sci 114(49); 12964-12969.
Macqueen DJ*, CR Primmer*, RD Houston* … JM Yáñez. The FAASG Consortium, 2017. Functional Analysis of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture. 2017. BMC Genomics 18:484
Grimholt U., H Hauge, A Germundsson-Hauge, JS Leong and BF Koop. 2015. Chemokine receptors and their duplications in Atlantic salmon. Dev. Comp. Immunol. 49:79-95
Rondeau EB, DR Minkley, JS Leong, AM Messmer, JR Jantzen, KR von Schalburg, NH Bird, BF Koop. 2014. The genome and linkage map for the Northern pike (Esox lucius): conserved synteny revealed between the salmonid sister group and the Neoteleostei. PLoS ONE 9(7):e102089
Sutherland BJG, KC Hanson, JR Jantzen, BF Koop, CT Smith. 2014. Divergent immunity and energetic programs in the gills of migratory and resident Oncorhynchus mykiss. Molec. Ecol. 23(8):1952-1964